A protracted pro-inflammatory state is a major contributing factor in the development,\nprogression and complication of the most common chronic pathologies. Fruit and vegetables represent\nthe main sources of dietary antioxidants and their consumption can be considered an efficient\ntool to counteract inflammatory states. In this context an evaluation of the protective effects of\nstrawberry extracts on inflammatory stress induced by E. coli LPS on human dermal fibroblast cells\nwas performed in terms of viability assays, ROS and nitrite production and biomarkers of oxidative\ndamage of the main biological macromolecules. The results demonstrated that strawberry extracts\nexerted an anti-inflammatory effect on LPS-treated cells, through an increase in cell viability, and the\nreduction of ROS and nitrite levels, and lipid, protein and DNA damage. This work showed for the\nfirst time the potential health benefits of strawberry extract against inflammatory and oxidative stress\nin LPS-treated human dermal fibroblast cells.
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